SmofKabiven | expertpncare

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The SmofKabiven® range is the latest generation of Fresenius Kabi’s 3CBs. It sets new handling and safety standards and provides clinical advantages from its composition and components (since 2018 in Indian market)
Available in different sizes with electrolytes, peripheral and central versions containing:
SMOFlipid®, benefits of the unique 4-oil combination
High amino acid content and providing taurine
Glucose for the provision of energy in the recommended ratio
Central - 986 ml, 1477 ml, 1970 ml
Peripheral - 1206 ml, 1448 ml, 1904 ml

SmofKabiven® is indicated as parenteral nutrition for adults and children aged 2 years and above when oral or enteral nutrition is impossible, insufficient or contraindicated.
SmofKabiven® can be used in patient requiring parenteral nutrition like patient undergoing major surgery, transplantation; critically ill patients; cancer patients; dialysis patients etc.
SmofKabiven® central is required in patients with requirements of high nitrogen and energy and in patients having central venous access (central line).
SmofKabiven® peripheral is required in patients with requirements of basic to moderate nitrogen and energy and can be given via peripheral venous access (peripharal line) as well.
SmofKabiven® can be given as Total Parenteral Nutrition (TPN) along with additives or as Supplemental Parenteral Nutrition (SPN) along with oral/enteral nutrition.

The dose should be individualised to the patient’s clinical condition, body weight (BW), nutritional and energy requirements, adjusting dosage based upon additional oral/enteral intake. It covers the need of the majority of the patients, but the dose should be based on the estimated ideal weight in obese patients.
SmofKabiven® Central:Admin. IV infusion into a central vein. Dosage range of 13-31 ml/kg bw/day will provide 0.6-1.6 g AAs/kg bw/day and 14-35 kcal/kg bw/day of total energy (12-27 kcal/kg bw/day of non-protein energy) and the recommended maximum daily dose is 35 ml/kg bw/day.Infusion rate should not exceed 2.0 ml/kg bw/h (adult & adolescents) with period of 14-24 hours and 2.4 ml/kg bw/h (Children (2-11 years) with period of 12-24 hours.
SmofKabiven® Peripheral:Admin. IV infusion into a peripheral or central vein.Dosage range of 20-40 ml/kg bw/day will provide 0.6-1.3 g AAs/kg bw/day and 14-28 kcal/kg bw/day of total energy (11-22 kcal/kg bw/day of non-protein energy) and the recommended maximum daily dose is 40 ml/kg bw/day.Infusion rate should not exceed 3.0 ml/kg bw/h with period of 14-24 hours (adult & adolescents) and 12-24 hours (Children (2-11 years).

The innovative 3-in-1 mix with fish oil:
Well-tolerated mixture of macronutrients and electrolytes based on SMOFlipid® and Aminoven® – just in one package system
SMOFlipid®
Positive impact on liver cell function and integrity
Favourable immune and inflammatory response
Reduced infectious complications and length of hospital stay
Controlled triglyceride levels
Favourable clinical outcome
Aminoven 10%
Provides high amounts of amino acids, suitable for increased requirements. Meets the requirements for essential AA (41.4 %) and BCAA (18.6 %)
Covers increased nitrogen demands without the risk of caloric overload for patients with moderate to severe illness
Prevent taurine deficiency in patients with sepsis, trauma, post-operative surgery, and long-term TPN without cysteine
Glucose - the carbohydrate component, completes SmofKabiven® to a unique mix of macronutrients
A moderate dose of glucose for the provision of energy in the recommended glucose-lipid ratio of 30-50% energy from lipids
Ratio of gm nitrogen to energy is
1:108 to 1:113, within recommended range of 1:100 to 1:150.0
Electrolytes : Supplementation of zinc prevents disturbances in wound healing and impairments in immune function & glucose tolerance
The innovative 3-in-1 mix with fish oil: The container – Big steps ahead with a bag
Sterile port membranes – enable first use without disinfection
Self-sealing and stable ports – simplify handling
Easily opening peel seals – facilitate handling
Easy handling, mixing and administration
Safe, convenient and time-saving use
Long shelf life at room temperature
(24 months at 20 – 25°C); no refrigerator needed Environment-friendly, lightweight material

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