Dipeptiven | expertpncare

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Available as N(2)-L-alanyl-L-glutamine dipeptide in 20% 50ml and 100 ml solution
Glutamine is conditionally essential amino acid for use in highly catabolic patients
Glutamine covers about 20% of total pool of free amino acids in the blood, while 40% - 60% in organs such as the liver and skeletal muscles.Glutamine should be part of amino acid supplementation in parenteral nutrition.
Dipeptide technology ensures stability on heat sterilization
Systemic role of glutamine:
Supports glutathione synthesis
Increases cellular defence mechanism
Fuel for enterocytes and immune cells
Is a nitrogen donor
Reduces insulin resistance

Dipeptiven 20%, 50ml and 100ml glass bottles
Depends on severity of the catabolic state & on amino acid requirement
1.5 - 2.5 ml (equivalent to 0.3 - 0.5 g)/kg BW/day. (=100 to 175 ml Dipeptiven for a patient of 70 kg body weight)
Rate of infusion should not exceed 0.1g amino acids/kg body wt./hr
Duration of use should not exceed 3 weeks
Not designed for direct administration
Should be mixed with a compatible amino acid carrier solution or an amino acid containing infusion regimen
A maximum daily dosage of 2 g amino acids per kg BW should not be exceeded in parenteral nutrition
Proportion of amino acid supplied through Dipeptiven should not exceed ~30% of total amino acid
Maximum daily dose: 2.5 ml or 0.5 g N(2)-L-alanyl-L-glutamine of Dipeptiven®/ kg BW.

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Dipeptiven (L-alanyl-L-glutamine). Summary of product characteristics